The relation of changes in intraoperative EEg and ECog with age, anamnesis duration and outcome of surgical treatment in children with symptomatic epilepsy

Aim. To reveal relation of change in intraoperative electroencephalography (EEG), electrocorticography (EсoG) with age patients, the anamnesis duration, localization and type pathology, result treatment. Materials methods. 64 patients symptomatic epilepsy operated at N.N. Burdenko National Medical Research Center Neurosurgery Ministry Health Russia from 2010 to 2016. 28 males, 36 females, 3 months 18 years, on average 7,2 years. The pathology localization: temporal – 21 cases, occipital parietal 18, frontal 25. Pathomorphology: 12 focal cortical dysplasia (FCD) I, 20 FCD II, 5 III, 4 tuberous sclerosis, low grade tumors, cases else. duration diseaseis 61 5081 days. Catamnesis (follow-up) ranged 364 1877 There was four criteria for including research: EEG, presence initial control registration EсoG, follow-up above are three hallmarks selected as significant concerning efficiency neurophysiological monitoring: 1) positive changes scalp EEG: decrease interhemispheric asymmetry due reduction slow activity side pathology; unilateral epileptiform bilateral if exist; 2) EсoG: regular activity; 3) absence or existence residual adjacent resected sites. statistical processing carried out application a Stat10 package. Results. more expressed dynamics EEG were revealed smaller already during operation. A correlation found between EEG. An inverse disease surgery (p = 0.1560). shown often seizure anamnesis. that ECoG occurred longer pathology. registered preservation seizures (outcomes 2, 3, 4, ILAE). Conclusions. During resective interventions children probability more, younger patient was. Intraoperative is one useful tools surgery, but it does not definitely determine success. no statistically relationship signs cortex removal area outcome surgical treatment seizures. Patients had times fewer areas cortex. dependence insignificant. Removal III tumors accompanied by complete elimination than level significance p 0.0305.